The major changes are in midfield and in goal. David Raya has been handed his Gunners debut between the sticks ahead of Aaron Ramsdale.
This is a huge surprise for us. Meanwhile, Fabio Vieira has been rewarded with a maiden start of the season after impressing of the bench.
Vieira won a penalty and assisted Nketiah’s goal against Fulham. He replicated the feat with a lovely assist for Jesus’ goal versus United this month.
The Portuguese has been rewarded for his efforts with a starting role ahead of Kai Havertz, who has looked short in form and confidence.
Confirmed Arsenal line-up (4-3-3): David Raya; Ben White, William Saliba, Gabriel Magalhaes, Oleksandr Zinchenko; Declan Rice, Fabio Vieira, Martin Odegaard; Bukayo Saka, Eddie Nketiah, Gabriel Martinelli.